Document Details

Document Type : Article In Journal 
Document Title :
Synthesis, Characterization, and In Vitro Antibacterial Activities of Macromolecules Derived from Bis-Chalcone
Synthesis, Characterization, and In Vitro Antibacterial Activities of Macromolecules Derived from Bis-Chalcone
 
Document Language : English 
Abstract : We investigated the antibacterial activity of some new macromolecules such as bis-pyrazoline, bis-pyrazole, bis-pyrimidines prepared from the reaction of bis-chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea. All the macromolecules have been characterized by IR, 1H NMR, 13C NMR, mass and elemental analyses. The antibacterial activity of these compounds was first tested in vitro by the disc diffusion assay against two Gram-positive and two Gram-negative bacteria, and then the minimum inhibitory concentration was determined with the reference to standard drug chloramphenicol. The results showed that pyrazoline derivative showed better antibacterial activity on S. typhimurium and E. coli than the reference drug chloramphenicol. 
ISSN : 0022-152X 
Journal Name : JOURNAL OF HETEROCYCLIC CHEMISTRY 
Volume : 49 
Issue Number : 6 
Publishing Year : 1433 AH
2012 AD 
Article Type : Article 
Added Date : Wednesday, July 12, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
A AsiriAsiri, A Researcher  
S KhanKhan, S Researcher  

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