Document Details Document Type : Article In Journal  Document Title : Bronchiolitis Obliterans Following Lung Transplantation Bronchiolitis Obliterans Following Lung Transplantation   Subject : Cardiothoracic Surgery  Document Language : English  Abstract : Bronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent studies suggest that immune injury is the main pathogenic event in small airway obliteration and the development of BOS. Early detection of BOS is possible as well as essential because prompt initiation of treatment may halt the progress of the disease and the development of chronic graft failure. Current treatment of BOS is disappointing despite advances in surgical techniques and improvements in immunosuppressive therapies. Therefore, a clear understanding of the pathogenesis of BOS plays a major role in the search for new and effective therapeutic strategies for better long-term survival and quality of life after lung transplantation  ISSN : 1010-7940  Journal Name : European Journal of Cardio-Thoracic Surgery  Volume : 30  Issue Number : 6  Publishing Year : 1427 AH 2006 AD  Article Type : Article  Added Date : Sunday, August 23, 2009  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email اسكندر القثمي Al-Githmi, Iskander Investigator Doctorate   Files File Name Type Description  20260.pdf pdf bronchiolitis obliterans following lung transplantation Back To Researches Page