|
Document Type |
: |
Article In Journal |
|
Document Title |
: |
Allergy Workup in Allergic Rhinitis Allergy Workup in Allergic Rhinitis |
|
Subject |
: |
Appropriate medical diagnosis and therapy of allergic rhinitis |
|
Document Language |
: |
English |
|
Abstract |
: |
Methods: This is a prospective cross-sectional study. Forty ne patients with symptoms and signs compatible with AR examined at the ENT clinic were sequentially included. AR diagnosis was confirmed at Allergy clinic by a positive reaction to an in-vivo tests: total peripheral eosinophil count (TPEC), total serum IgE, and specific IgE antibodies to common inhalant allergens by immuno-CAP system (Phadiatop).
Results: AR confirmed by positive SPT was detected in 30 cases (73%). Their ages ranged between 16-52 years old (m3n 27 ±9SD), and females constituted 56%. The predominant allergens were house dust mites (HDMs): Dermatophagoides pteronyssinus 70% and D. farinae 67%, Cat 33%, Cockroach 33%, Salsola pestifer 23%, and Aspergilus 20%. TPEC ranged 50 – 1210 cell/mm3 (mean=299 ±295SD), and eosinophilia (?450 cells/mm3) was found in 23%. Toral IgE ranged 8 – 2000 IU/ml (mean = 354 ±452SD, and was elevated (> 190 IU/ml) in 53%. Phadiatop was positive in 83% of AR cases. A very significant correlation between SPT and Phadiatop (df=1, P<0.001) was found.
Conclusion: Sensitization to inhalant allergens, particularly HDMs, by both in-vivo (SPT) and in-vitro (Phadiatop) methods was common in AR cases in Jeddah. The presence of eosinophilia and/or high total IgE in the context of compatible clinical findings may be helpful in establishing the diagnosis of AR. This work advocates the importance of allergy workup for allergen sensitization in both AR diagnosis and the subsequent care of patines by promoting avoidance strategies.
Keynotes: Allergic rhinitis, Eosinophilia, IgE, Phadiatop, Skin prick est. |
|
ISSN |
: |
1319-1004 |
|
Journal Name |
: |
Medical Science Journal |
|
Volume |
: |
7 |
|
Issue Number |
: |
2 |
|
Publishing Year |
: |
2003 AH
2003 AD |
|
Article Type |
: |
Article |
|
Added Date |
: |
Sunday, October 4, 2009 |
|
Researchers
| طارق جمال | طارق جمال | Researcher | Doctorate | |
|
Files
|
20816.doc
| doc | Allergy Workup in Allergic Rhinitis |
|