Document Details

Document Type : Article In Journal 
Document Title :
Possible Involvement of Endogenous Opioid Peptides in the Mechanism of Dantrolene Actions
Possible Involvement of Endogenous Opioid Peptides in the Mechanism of Dantrolene Actions
 
Subject : Pharmacology 
Document Language : English 
Abstract : The effects of dantrolene on the release of opioid substances were studied in three different biological systems. It was observed that dantrolene possesses an antinociceptive activity, and an inhibitory action on the contractions of the rabbit's jejunum, and frog's rectus abdominis muscles. All of these actions were antagonised by naloxone in a noncompetitive manner. These observations may indicate that endogenous opioids are involved in the mechanism of dantrolene actions 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 2 
Issue Number : 1 
Publishing Year : 1412 AH
1992 AD 
Article Type : Article 
Added Date : Thursday, March 31, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
أسامة طيبTayeb, Osama ResearcherDoctorate 

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 29442.pdf pdf 

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