Document Details

Document Type : Article In Journal 
Document Title :
Determination of insulin resistance in non-diabetic Saudi adults by including fasting free fatty acids into QUICKI
Determination of insulin resistance in non-diabetic Saudi adults by including fasting free fatty acids into QUICKI
 
Subject : Endocrinology 
Document Language : English 
Abstract : Most available diagnostic methods of insulin resistance are either unsuitable for screening or fail to detect marginal cases. It was reported that including plasma free fatty acids (FFA) into QUICK (quantitative insulin sensitivity check index) I improves its diagnostic power. The aim was to test the effectiveness of modified QUICK I against HOMA (homeostasis model assessment) and QUICK I in identifying insulin resistant subjects in the non-diabetic adult population. 357 healthy adults aged 18 - 50 years were recruited randomly. Their anthropometric and demographic information were taken. Biochemical parameters and FFA (free fatty acid) were measured in fasting blood samples and used to calculate modified QUICK I. Reported cut-off point was used to identify IR subjects, who were matched for age and sex to individuals from the rest of the subjects. 209 subjects satisfied the criteria. 97 individuals were identified to be IR. This group had statistically different anthropometric and biochemical parameters compared to NIR group. Biochemical parameters did not differ significantly when QUICK I was used to identify IR subjects. The modified QUICK I for all subjects correlated significantly (p = 0.01) with HOMA values (r = -0.756) and with QUICK I values (r = 0.758). Modified QUICK I is a more powerful diagnostic index of IR in Saudi non diabetic adults 
ISSN : 2006-9723 
Journal Name : International Journal of Medicine and Medical Sciences 
Volume : 1 
Issue Number : 9 
Publishing Year : 1430 AH
2009 AD 
Article Type : Article 
Added Date : Friday, December 2, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ايمان العيسىAlissa, Eman InvestigatorDoctorate 
سهاد باحجريBahijri, Suhad ResearcherDoctorate 
دعد أكبرAkbar, Daad ResearcherDoctorate 
توفيق غبرهGhabrah, Tawfik ResearcherDoctorate 

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