Document Details

Document Type : Thesis 
Document Title :
Evaluation of Inhibitory Effect of Different Probiotic Strains on Salivary Mutans Streptococci Count in Experimental Rats Randomized Control Animal Study
البكتيريا البروبيوتيك علي تعداد المكورات السبحية الطفرية العقدية في فئران التجارب
 
Subject : Faculty of Dentistry - department of pediatric dentestry 
Document Language : Arabic 
Abstract : Objectives: The present study was carried out to investigate the inhibitory effect of five different Probiotic Strains on salivary mutans streptococcus and to evaluate survival rate of probiotic strains in the oral flora. Materials and Methodology: saliva samples for isolation of streptococcus mutans used in this study were obtained from volunteer patients. Informed written consents were obtained from the parents perior to sampling from children that matched criteria of selection. Biolog system test for identification of isolated streptococcus mutans used for infection of albino rats. The rats (n=42) were randomly divided according to the type of diet given into 7 groups (n=6). T1: Fermented milk without any probiotic strain, T2: Fermented milk containing Lactobacillus acidophilus, T3: Fermented milk containing Lactobacillus plantarum, T4: Fermented milk containing Lactobacillus reuteri ATCC, T5: Fermented milk containing Lactobacillus rhamnosus ATCC, T6: Fermented milk containing Bifidobacterium bifidium NCTC. Rats were housed up to five weeks where saliva samples were collected from rats' oral cavities at the end of each week to evaluate the inhibitory effect of different probiotics by counting the streptococcus mutans. Counting of lactobacilli and Bifidobacteria in rats' saliva was done every week for all experiment period to evaluate their survival rate. Result: We found that streptococcus mutans count was significantly decreased in group T3, T4, T5, and T6 with varying degrees where group T4 showed the statistically significant lowest S. mutans mean count followed by T5 (P-value<0.001). Group C and T1 showed a statistically significant highest in streptococcus mutans mean count. Conclusion and Recommendations: Different Probiotic strains showed an inhibitory effect against streptococcus mutans count with varying degrees. Milk containing lactobacilli reuteri could be one of the best dietary regimens for dental caries prevention. Keywords: probiotic, streptococcus mutans, lactobacilli, bifidobacterium, rats 
Supervisor : DR. Samar Madany Alagy 
Thesis Type : Master Thesis 
Publishing Year : 1437 AH
2016 AD 
Added Date : Monday, July 25, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ريما مهدي الحسينAlhusain, Reema MahdiResearcherMaster 

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