Document Details

Document Type : Thesis 
Document Title :
ANTIBACTERIAL ACTIVITY OF NANOPARTICLES (QUANTUM DOTS) FOR TREATMENT OF WOUND INFECTION
نشاط جزيئات النانو (كوانتم دوتس) المضادة للبكتيريا لعلاج عدوى الجروح
 
Subject : Faculty of Applied Medical Sciences 
Document Language : Arabic 
Abstract : Antibiotics are one of the most important drugs in fighting bacterial infection and have a significant role in the maintenance of public health. Wound infection is responsible for a higher percentage of morbidity and contributes to aggravate in health care costs. Antibiotics are the preferable way to prevent wound infection. In recent decades, these drugs become less effective against many bacteria such as Methicillin Resistant Staphylococcus aureus (MRSA), Escherichia coli and Pseudomonas aeruginosa. Therefore, to overcome the major disadvantages related to antibiotics resistance pathogenic microorganisms, developments in nanotechnology have opened new areas in nanomedicine that allow for synthesis of nanoparticles, which can be assembled into complex architectures. Using of nanoparticles with novel synthesis has economic and eco-friendly benefits and may give new source of antibacterial agent with the possible novel mechanism of action. In addition to that, inorganic antibacterial agent such as titanium and zinc have advantages over organic compound due to their stability and safety. In this study, quantum dots were synthesized, chemically and physically characterized, and their antibacterial activity were investigated. The nanoparticles were tested in a dose response strategy against three of the most common pathogenic bacteria, Methicillin Resistance Staphylococcus aureus (MRSA), E. coli and Pseudomonas aeruginosa that cause wound infection. The main finding of this result revealed that the synthesized quantum dots were not only are capable to kill the pathogenic bacteria in a short period of time but, they are strain specific in some cases. The impact of this project will give new strategies in treatment of wound infection. 
Supervisor : Dr. Hani Alhadrami 
Thesis Type : Master Thesis 
Publishing Year : 1439 AH
2017 AD 
Added Date : Thursday, November 23, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عائشة محمد باقاسيBaqasi, Aisha MohammadResearcherMaster 

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